Michael Hadjiargyrou is a molecular and cell biologist. His research focuses on understanding the development and regeneration of the musculoskeletal system. Specifically, he seeks to develop innovative approaches for engineering new musculoskeletal tissue using knowledge derived from basic molecular/cellular biology and biomaterials.
Hadjiargyrou received his training in molecular and cell biology at the City University of New York and completed his post-doctoral fellowship at the California Institute of Technology. Prior to joining New York Tech, he served as assistant and associate professor in the Department of Biomedical Engineering at Stony Brook University as well as graduate program director and associate vice president for research. He is a member of the American Society for Bone and Mineral Research and the Federation of American Societies for Experimental Biology, and serves on the editorial Board of a number of scientific journals.
Recent Projects and Research
- Transcriptional Profiling of Bone Regeneration
- Discovery and characterization of Mustn1
- The role of HIF-1a and apoptosis on bone regeneration
- Biomimetic electrospun scaffolds for tissue engineering
- MicroRNA mechanisms during fracture repair
- Hadjiargyrou, M., Lombardo, F., Zhao, S., Ahrens, W., Joo, J., Ahn, H., Jurman, M., White, D.W. and Rubin, C.T. (2002) Transcriptional profiling of bone regeneration: Insight into the Molecular Complexity of Wound Repair. J. Biol. Chem. 277:30177-30182.
- Luu, Y.K., Kim, K., Hsiao, B.S., Chu, B. and Hadjiargyrou, M. (2003) Development of a nanostructured DNA delivery scaffold via electrospinning of PLGA and PLA-PEG block copolymers. J. Control Release 89:341-353.
- Lombardo, F., Komatsu, D., and Hadjiargyrou, M. (2004) Molecular cloning and characterization of Mustang, a novel nuclear protein expressed during bone development and regeneration. The FASEB Journal 18:52-61.
- Komatsu, D., Bosch-Marce, M., Semenza, G.L. and Hadjiargyrou, M. (2007) Enhanced Bone Regeneration Associated with Decreased Apoptosis in Mice with Partial HIF-1a Deficiency. J. Bone Miner. Res. 22:366-374.
- Hadjiargyrou, M. and O’Keefe, RJ. (2014) The convergence of fracture repair and stem cells: interplay of genes, aging, environmental factors and disease. J. Bone Miner. Res. 29:2307-2322.
Honors and Awards
- 2014, Mentor of the Year, New York Tech Student Government Association
- 2008, Most Cited Paper Award (2004), Journal of Controlled Release
- 2003, Outstanding Teacher of the Year Award, Department of Biomedical Engineering, Stony Brook University
- 1992, American Heart Association Research Fellowship, Division of Biology, California Institute of Technology
- 1986, Presidential Prize for Academic Excellence in Philosophy, Baruch College, City University of New York
Courses Taught at New York Tech
- General Biology I
- Genetic Engineering
- Cell Biology
- Biomedical Research I, II and III