Throughout his career, Kurt Amsler has focused his research on epithelial physiology, with a particular emphasis on renal physiology. His research has covered multiple areas including basic epithelial transport physiology, cystic fibrosis, polycystic kidney disease and, most recently, acute kidney injury. He has received research funding from the NIH, the American Heart Association, the Cystic Fibrosis Foundation, and other organizations to support his research activities. His teaching areas of expertise include physiology and renal pathophysiology. Amsler is also a member of several national societies including the American Society of Cell Biology, the American Physiological Society, and the American Society of Nephrology. He has served on multiple national committees for these societies, and has served as a grant reviewer for the NIH, the NSF, the American Heart Association, and other philanthropic foundations. He has reviewed submitted manuscripts for a wide range of peer-reviewed scientific journals.
Amsler obtained his B.A. from New College (Sarasota, FL) in Biology, his M.Sc. from the University of Toronto (Toronto, Ontario, Canada) in Medical Sciences, and his Ph.D. from the University of Tennessee-Oak Ridge Graduate School of Biomedical Sciences in Biomedical Sciences. Following his graduate work, he was a Postdoctoral Fellow in the laboratory of Dr. E.A. Adelberg at the Yale University School of Medicine, and a Postdoctoral Fellow under Dr. R.K.H. Kinne at the Max-Planck-Institute for System Physiology. Amsler’s previous faculty positions included Assistant Professor in the Department of Physiology, Mt. Sinai School of Medicine, Assistant Professor in the Department of Physiology, UMDNJ-Robert Wood Johnson Medical School, Assistant Professor, Division of Nephrology, Department of Medicine, Mt. Sinai School of Medicine, and Associate Professor, Division of Nephrology, Department of Medicine, Mt. Sinai School of Medicine. He has also worked for a period at a biotech startup company as the director of the Biology Division.
- Regulation of renal paracellular permeability in acute kidney injury
- Janosevic D, Axis J, Bacallao RL, Amsler K. 2015. Occludin content modulates hydrogen peroxide-induced increase in renal epithelial paracellular permeability. J Cell Biochem 2015 Sep 8. doi: 10.1002/jcb.25362
- Caswell D, Jaggi S, Axis J, Amsler K. 2013. Src family kinases regulate renal epithelial paracellular permeability barrier in an occludin-independent manner. J Cell Physiol 228:1210. doi: 10.1002/jcp.24274
- Israeli S, Amsler K, Zheleznova N, Wilson PD. 2010. Abnormalities in focal adhesion complex formation, regulation, and function in human autosomal recessive polycystic kidney disease epithelial cells. Am J Physiol 298:C831. doi: 10.1152/ajpcell.00032.2009.
Honors + Awards
- 2012-2015 NIDDK, 1 R15 DK091749-01A1, PI – Kurt Amsler, “Src Family Kinases and Control of Epithelial Paracellular Permeability”
Courses I Teach/Have Taught at NYIT
- Advanced Concepts of Neuromusculoskeletal Sciences
- Lectures on epithelial transport physiology