Jayme D. Mancini, D.O., Ph.D uses her training in Family Medicine and Osteopathic Manipulative Medicine (OMM) to address health and quality of life using OMM, therapeutic injections, and nutrition and exercise counseling. She has a Ph.D. in Neuroscience, studying cellular development. Currently, she does osteopathic clinical and translational research. Her special interests include neurological disorders, connective tissue disorders, pediatrics, and sports and outdoor recreation injuries.

Recent Projects/Research

Her research investigates how osteopathic manipulative medicine (OMM) can best be used to manage central nervous system disorders and connective tissue disorders. She uses a translational approach to determine the relationships between the clinical effects of OMM and the underlying mechanisms. The mechanisms she currently measures include the microbiome in Parkinson's disease and factors involved in healing from injuries such as concussion and sprains. Osteopathic approach to care often involves OMM, which includes the examination and treatment of the neuromusculoskeletal system physiology with our hands to improve body mechanics such as unstable joints, muscle tone, circulation of body fluids, and decompressing nerves.


  • Li TS and Mancini JD. "Integrative approach to Parkinson’s disease" Alternative and Complementary Therapies 23(1)2017
  • DiFrancisco-Donoghue J, Apoznanskib T, de Vries K, Jung MK, Mancini J, and Yao S. "Osteopathic manipulation as a complementary approach to Parkinson’s disease: A controlled pilot study" NeuroRehabilitation :40 (2017) pg 145-15
  • Mancini JD and Varkey A. "Integration of Osteopathic Manual Treatments in the Management of Foot Dystonia in Parkinson’s Disease: A Case Series" Int J Neurorehabilitation Eng 2016, 3:6
  • Halimi M, Leder A, and Mancini J. "Integration of osteopathic manual treatments in management of cervical dystonia with tremor: A case series" Tremor and other hyperkinetic disorders 2016
  • Bradford AB, Mancini JD, Atchison WD. "Methylmercury-associated increases in Fluo-4 fluorescence in neonatal rat cerebellar slices are dependent on granule cell migrational stage and modulated by GABA(A) receptors" J Pharmacol Exp Ther. 2015 Oct 29

Honors & Awards

Jayme D. Mancini, D.O., Ph.D. was a Panel Judge for the American Academy of Osteopathy LBORC Annual Research Proposal and Mentorship Grand Rounds 2019.

Course Taught at New York Tech

  • Osteopathic Manipulative Medicine

Contact Info