Claude Gagna, Ph.D.

Faculty Profile - Department of Life Sciences

Claude Gagna, Ph.D.
Associate Professor
E-mail: cgagna@nyit.edu

Education

Ph.D. in Anatomy (Biochemistry). New York University, New York, N.Y.
Postdoctoral Fellowship (Natural Sciences), Dept. of Biochemistry, New York University, N.Y.
Postdoctoral Fellowship (Molecular Biology), Dept. of Physiology, University of Medicine of New Jersey, Newark, N.J.
M.S. in Anatomy (Biochemistry), Fairleigh Dickinson University, Hackensack, N.J.
B.S. in Biology, Saint Peters College, Jersey City, N.J.

Academic & Clinical Appointments

1999–Present  Associate Professor, Dept. of Life Sciences, NYIT
Assistant Professor, Dept. of Pathology, University of Medicine & Dentistry, N.J.
Assistant Professor, School of Medicine, University of Medicine & Dentistry, N.J.
Assistant Professor, Department of Natural Sciences, Fairleigh Dickinson University, N.J.

Professional Certification

FAIC: Fellow American Institute of Chemists. American Institute of Chemists, Bethesda, Md.
CChem MRSC: Member Royal Society of Chemistry. RSC, Cambridge, U.K.
ChE: American Institute of Chemical Engineers, New York, N.Y.

Academic And Professional Honors

Leonardo DaVinci Award for Achievement in Science
Faculty Scholars Reception Award, NYIT
Deans "Award for Outstanding Research", NYIT

Research Interests

My research involves the examination of B-DNA, Z-DNA, triplex DNA and quadruplex DNA in the normal and abnormal tissues. My final goal is the development of a nonsurgical treatment for human cataracts, skin cancer and regulating various oncogenes, using DNA (RNA) and small molecule drug probes.Additionally, I have developed two new genomics approaches towards disease, viz.,''transitional structural chemogenomics" and "transitional structural chemoproteomics". My research involves DNA-RNA-Protein nanotechnology, with the production of novel nucleic acid and tissue microarrays. I am also active in both DNA nanotechnology (bio-medical devices)and DNA nanoelectronics,viz.,next generation DNA computer chips.

Current Professional Activities

American Medical Association.Biophysical Society
American Society for Biochemistry and Molecular Biology
American Association of Anatomists. American Chemical Society
Royal Society of Chemistry.Human Genome Organization
American Institute of Chemical Engineering
American Association of University Professors

Selected Journal Articles-Original Papers

C.E.Gagna, et.al.(1997). The Localization of B-DNA and Z-DNA in Terminaly Differentiating Fiber Cells in the Adult Lens. J. Histochem. Cytochem. 45:1511-1521.
C.E.Gagna, et.al.(2001). Comparison of Apoptosis and Terninal Differentiation: The Mammalian Aging Process. J. Histochem Cytochem. 49:929-9310.
C.E.Gagna, et.al.(2003). The Halting Arrival of Left-Handed Z-DNA. Med. Hypothesis. 60:418-423.

Patents and Pending Patents

Multi-Stranded DNA (RNA) Microarray:U.S.Patent No.60/308,936
International Patent No. W02003012124
European Patent No. F81855PCTEP
Japanese Patent No. K-T104-209